Entry Detail



General Information

Database ID:SKCM08718
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:DENND4A
Full Name:DENN domain containing 4A
Category:mRNA
Synonyms:IRLB|MYCPBP
Chromosome:chr15
Strand:-
Coordinate:
Start Site(bp):65658046End Site(bp):65792293
Gene Summary:This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016]
External Links:
Ensembl ID:ENSG00000174485
HGNC ID:HGNC:24321
Entrez Gene:10260



Expression Profile of DENND4A Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-106a-5p
YES
YES
NO
hsa-miR-106b-5p
YES
YES
NO
hsa-miR-150-5p
NO
YES
YES
hsa-miR-15a-5p
NO
YES
YES
hsa-miR-15b-5p
NO
YES
YES
hsa-miR-16-5p
NO
YES
YES
hsa-miR-17-5p
YES
YES
NO
hsa-miR-195-5p
NO
YES
YES
hsa-miR-20a-5p
YES
YES
NO
hsa-miR-20b-5p
YES
YES
NO
hsa-miR-300
YES
YES
NO
hsa-miR-374a-5p
NO
YES
YES
hsa-miR-374b-5p
NO
YES
YES
hsa-miR-381-3p
YES
YES
NO
hsa-miR-424-5p
NO
YES
YES
hsa-miR-497-5p
NO
YES
YES
hsa-miR-519d-3p
YES
YES
NO
hsa-miR-93-5p
YES
YES
NO
Display: