ctcRbase

Entry Detail

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General Information

Database ID: SKCM08725 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: N4BP2 Full Name: NEDD4 binding protein 2 Category: mRNA Synonyms: B3BP Chromosome: chr4 Strand: + Coordinate: Start Site(bp): 40056826 End Site(bp): 40158252 Gene Summary: This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed, developmentally downregulated 4, (Nedd4) proteins. This protein binds and hydrolyzes ATP, may function as a 5'-polynucleotide kinase, and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016] External Links: Ensembl ID: ENSG00000078177 HGNC ID: HGNC:29851 Entrez Gene: 55728

Expression Profile of N4BP2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-216a-5p NO YES YES hsa-miR-216b-5p NO YES YES hsa-miR-217 YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-379-5p YES YES NO hsa-miR-410-3p YES YES NO Display: