Entry Detail



General Information

Database ID:SKCM08771
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:CNKSR2
Full Name:connector enhancer of kinase suppressor of Ras 2
Category:mRNA
Synonyms:CNK2|KSR2|MAGUIN|MRXSHG
Chromosome:chrX
Strand:+
Coordinate:
Start Site(bp):21374418End Site(bp):21654695
Gene Summary:This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
External Links:
Ensembl ID:ENSG00000149970
HGNC ID:HGNC:19701
Entrez Gene:22866



Expression Profile of CNKSR2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
Display:N/A