Entry Detail



General Information

Database ID:SKCM08784
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:CTC1
Full Name:CST telomere replication complex component 1
Category:mRNA
Synonyms:AAF-132|AAF132|C17orf68|CRMCC|tmp494178
Chromosome:chr17
Strand:-
Coordinate:
Start Site(bp):8224821End Site(bp):8248044
Gene Summary:This gene encodes a component of the CST complex. This complex plays an essential role in protecting telomeres from degradation. This protein also forms a heterodimer with the CST complex subunit STN1 to form the enzyme alpha accessory factor. This enzyme regulates DNA replication. Mutations in this gene are the cause of cerebroretinal microangiopathy with calcifications and cysts. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Mar 2012]
External Links:
Ensembl ID:ENSG00000178971
HGNC ID:HGNC:26169
Entrez Gene:80169



Expression Profile of CTC1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-103a-3p
YES
YES
NO
hsa-miR-107
YES
YES
NO
hsa-miR-124-3p
NO
YES
YES
hsa-miR-29a-3p
YES
YES
YES
hsa-miR-29b-3p
YES
YES
YES
hsa-miR-29c-3p
YES
YES
YES
hsa-miR-329-3p
YES
NO
NO
hsa-miR-362-3p
YES
NO
NO
hsa-miR-424-5p
YES
YES
NO
hsa-miR-876-5p
NO
YES
YES
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