ctcRbase

Entry Detail

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General Information

Database ID: SKCM08809 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SPTLC2 Full Name: serine palmitoyltransferase long chain base subunit 2 Category: mRNA Synonyms: HSN1C|LCB2|LCB2A|NSAN1C|SPT2|hLCB2a Chromosome: chr14 Strand: - Coordinate: Start Site(bp): 77505997 End Site(bp): 77616773 Gene Summary: This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011] External Links: Ensembl ID: ENSG00000100596 HGNC ID: HGNC:11278 Entrez Gene: 9517

Expression Profile of SPTLC2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-128-3p YES NO YES hsa-miR-132-3p YES YES NO hsa-miR-133a-3p YES NO YES hsa-miR-133b YES NO YES hsa-miR-137 YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-149-5p YES NO YES hsa-miR-17-5p YES YES NO hsa-miR-186-5p YES NO YES hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-24-3p YES NO YES hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-30a-5p YES NO YES hsa-miR-30b-5p YES NO YES hsa-miR-30c-5p YES NO YES hsa-miR-30d-5p YES NO YES hsa-miR-30e-5p YES NO YES hsa-miR-320a YES NO YES hsa-miR-320b YES NO YES hsa-miR-320c YES NO YES hsa-miR-320d YES NO YES hsa-miR-324-3p YES NO NO hsa-miR-330-3p YES NO NO hsa-miR-340-5p YES NO YES hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-452-5p YES NO YES hsa-miR-455-5p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-758-3p YES YES YES hsa-miR-876-5p YES YES NO hsa-miR-93-5p YES YES NO hsa-miR-9-5p YES YES YES Display: