ctcRbase

Entry Detail

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General Information

Database ID: SKCM08816 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: UVRAG Full Name: UV radiation resistance associated Category: mRNA Synonyms: DHTX|VPS38|p63 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 75815167 End Site(bp): 76143195 Gene Summary: This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000198382 HGNC ID: HGNC:12640 Entrez Gene: 7405

Expression Profile of UVRAG Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-136-5p YES YES NO hsa-miR-145-5p YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-25-3p YES YES YES hsa-miR-302a-3p YES NO YES hsa-miR-302b-3p YES NO YES hsa-miR-302c-3p YES NO YES hsa-miR-302d-3p YES NO YES hsa-miR-302e YES NO YES hsa-miR-32-5p YES YES YES hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-369-3p YES NO YES hsa-miR-372-3p YES NO YES hsa-miR-373-3p YES NO YES hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-422a YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-520a-3p YES NO YES hsa-miR-520b YES NO YES hsa-miR-520c-3p YES NO YES hsa-miR-520d-3p YES NO YES hsa-miR-520e YES NO YES hsa-miR-599 YES YES NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES Display: