Entry Detail



General Information

Database ID:SKCM08823
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:EXOC4
Full Name:exocyst complex component 4
Category:mRNA
Synonyms:SEC8|SEC8L1|Sec8p
Chromosome:chr7
Strand:+
Coordinate:
Start Site(bp):133253073End Site(bp):134066589
Gene Summary:The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000131558
HGNC ID:HGNC:30389
Entrez Gene:60412



Expression Profile of EXOC4 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-1271-5p
YES
YES
NO
hsa-miR-134-5p
YES
YES
NO
hsa-miR-136-5p
YES
YES
NO
hsa-miR-149-5p
YES
YES
NO
hsa-miR-182-5p
YES
YES
NO
hsa-miR-204-5p
YES
YES
NO
hsa-miR-211-5p
YES
YES
NO
hsa-miR-214-3p
YES
YES
NO
hsa-miR-217
YES
YES
NO
hsa-miR-219a-5p
YES
YES
NO
hsa-miR-23a-3p
YES
YES
NO
hsa-miR-23b-3p
YES
YES
NO
hsa-miR-30a-5p
YES
YES
NO
hsa-miR-30b-5p
YES
YES
NO
hsa-miR-30c-5p
YES
YES
NO
hsa-miR-30d-5p
YES
YES
NO
hsa-miR-30e-5p
YES
YES
NO
hsa-miR-382-5p
YES
YES
YES
hsa-miR-384
YES
YES
NO
hsa-miR-503-5p
YES
YES
NO
hsa-miR-873-5p
YES
YES
NO
hsa-miR-96-5p
YES
YES
NO
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