Entry Detail



General Information

Database ID:SKCM08826
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:MORC2
Full Name:MORC family CW-type zinc finger 2
Category:mRNA
Synonyms:CMT2Z|ZCW3|ZCWCC1
Chromosome:chr22
Strand:-
Coordinate:
Start Site(bp):30925130End Site(bp):30968298
Gene Summary:This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The protein has been found to regulate the activity of ATP citrate lyase via specific interaction with this enzyme in the cytosol of lipogenic breast cancer cells. The protein also plays a role in lipogenesis and adipocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
External Links:
Ensembl ID:ENSG00000133422
HGNC ID:HGNC:23573
Entrez Gene:22880



Expression Profile of MORC2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-186-5p
YES
YES
YES
hsa-miR-18a-5p
YES
YES
NO
hsa-miR-18b-5p
YES
YES
NO
hsa-miR-296-3p
YES
YES
NO
hsa-miR-340-5p
YES
YES
YES
hsa-miR-7-5p
YES
YES
NO
Display: