Entry Detail



General Information

Database ID:SKCM08847
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:ABCB8
Full Name:ATP binding cassette subfamily B member 8
Category:mRNA
Synonyms:EST328128|M-ABC1|MABC1
Chromosome:chr7
Strand:+
Coordinate:
Start Site(bp):151028422End Site(bp):151047782
Gene Summary:This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
External Links:
Ensembl ID:ENSG00000197150
HGNC ID:HGNC:49
Entrez Gene:11194



Expression Profile of ABCB8 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
Display:N/A