ctcRbase

Entry Detail

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General Information

Database ID: SKCM08860 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PIAS3 Full Name: protein inhibitor of activated STAT 3 Category: mRNA Synonyms: ZMIZ5 Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 145848522 End Site(bp): 145859836 Gene Summary: This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000131788 HGNC ID: HGNC:16861 Entrez Gene: 10401

Expression Profile of PIAS3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1-3p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-206 YES YES NO hsa-miR-328-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-455-5p YES YES NO hsa-miR-496 YES YES NO hsa-miR-543 YES YES NO hsa-miR-613 YES YES NO Display: