Entry Detail



General Information

Database ID:SKCM08873
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:KLHL9
Full Name:kelch like family member 9
Category:mRNA
Synonyms:-
Chromosome:chr9
Strand:-
Coordinate:
Start Site(bp):21329671End Site(bp):21335380
Gene Summary:This gene encodes a protein that belongs to the kelch repeat-containing family, and contains an N-terminal BTB/POZ domain, a BACK domain and six C-terminal kelch repeats. The encoded protein is a component of a complex with cullin 3-based E3 ligase, which plays a role in mitosis. This protein complex is a cell cycle regulator, and functions in the organization and integrity of the spindle midzone in anaphase and the completion of cytokinesis. The complex is required for the removal of the chromosomal passenger protein aurora B from mitotic chromosomes. [provided by RefSeq, Jul 2016]
External Links:
Ensembl ID:ENSG00000198642
HGNC ID:HGNC:18732
Entrez Gene:55958



Expression Profile of KLHL9 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-129-2-3p
YES
NO
YES
hsa-miR-133a-3p
YES
YES
YES
hsa-miR-133b
YES
YES
YES
hsa-miR-136-5p
YES
YES
NO
hsa-miR-141-3p
YES
YES
NO
hsa-miR-147a
YES
NO
NO
hsa-miR-182-5p
YES
YES
YES
hsa-miR-200a-3p
YES
YES
NO
hsa-miR-218-5p
YES
YES
NO
hsa-miR-219a-5p
YES
YES
NO
hsa-miR-296-3p
YES
YES
NO
hsa-miR-300
YES
YES
NO
hsa-miR-326
YES
YES
NO
hsa-miR-329-3p
YES
NO
NO
hsa-miR-330-5p
YES
YES
NO
hsa-miR-340-5p
YES
YES
YES
hsa-miR-362-3p
YES
NO
NO
hsa-miR-376c-3p
YES
YES
NO
hsa-miR-377-3p
YES
YES
YES
hsa-miR-379-5p
YES
YES
NO
hsa-miR-381-3p
YES
YES
NO
hsa-miR-382-5p
YES
YES
NO
hsa-miR-384
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-485-5p
YES
YES
NO
hsa-miR-873-5p
YES
YES
NO
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