ctcRbase

Entry Detail

---



General Information

Database ID: SKCM08941 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: USB1 Full Name: U6 snRNA biogenesis phosphodiesterase 1 Category: mRNA Synonyms: C16orf57|HVSL1|Mpn1|PN|hUsb1 Chromosome: chr16 Strand: + Coordinate: Start Site(bp): 57999546 End Site(bp): 58021618 Gene Summary: This gene encodes a protein with several conserved domains, however, its exact function is not known. Mutations in this gene are associated with poikiloderma with neutropenia (PN), which shows phenotypic overlap with Rothmund-Thomson syndrome (RTS) caused by mutations in the RECQL4 gene. It is believed that this gene product interacts with RECQL4 protein via SMAD4 proteins, explaining the partial clinical overlap between PN and RTS. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2011] External Links: Ensembl ID: ENSG00000103005 HGNC ID: HGNC:25792 Entrez Gene: 79650

Expression Profile of USB1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-128-3p YES YES NO hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-542-3p YES YES NO Display: