ctcRbase

Entry Detail

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General Information

Database ID: SKCM08953 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: INSIG2 Full Name: insulin induced gene 2 Category: mRNA Synonyms: INSIG-2 Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 118088452 End Site(bp): 118110997 Gene Summary: The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000125629 HGNC ID: HGNC:20452 Entrez Gene: 51141

Expression Profile of INSIG2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-1271-5p YES YES YES hsa-miR-139-5p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-147a YES NO NO hsa-miR-182-5p YES YES YES hsa-miR-183-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-200a-3p YES YES NO hsa-miR-217 YES YES NO hsa-miR-219a-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-300 YES YES YES hsa-miR-324-5p YES NO YES hsa-miR-32-5p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-375 YES YES YES hsa-miR-381-3p YES YES YES hsa-miR-382-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-520f-3p YES NO YES hsa-miR-543 YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-758-3p YES YES NO hsa-miR-7-5p YES YES YES hsa-miR-875-5p YES YES YES hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO hsa-miR-96-5p YES YES YES Display: