ctcRbase

Entry Detail

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General Information

Database ID: SKCM08981 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: FBXO46 Full Name: F-box protein 46 Category: mRNA Synonyms: 20D7-FC4|FBXO34L|Fbx46 Chromosome: chr19 Strand: - Coordinate: Start Site(bp): 45710629 End Site(bp): 45730904 Gene Summary: Members of the F-box protein family, such as FBXO46, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] External Links: Ensembl ID: ENSG00000177051 HGNC ID: HGNC:25069 Entrez Gene: 23403

Expression Profile of FBXO46 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-138-5p YES YES YES hsa-miR-143-3p YES NO YES hsa-miR-144-3p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-22-3p YES YES YES hsa-miR-27a-3p YES NO YES hsa-miR-27b-3p YES NO YES hsa-miR-340-5p YES NO YES hsa-miR-346 YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-421 YES YES NO hsa-miR-423-5p YES NO NO hsa-miR-495-3p YES YES YES Display: