Entry Detail



General Information

Database ID:SKCM09002
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:PPME1
Full Name:protein phosphatase methylesterase 1
Category:mRNA
Synonyms:PME-1
Chromosome:chr11
Strand:+
Coordinate:
Start Site(bp):74171099End Site(bp):74254703
Gene Summary:This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
External Links:
Ensembl ID:ENSG00000214517
HGNC ID:HGNC:30178
Entrez Gene:51400



Expression Profile of PPME1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-1271-5p
YES
YES
NO
hsa-miR-128-3p
YES
YES
NO
hsa-miR-182-5p
YES
YES
NO
hsa-miR-214-3p
YES
YES
NO
hsa-miR-216a-5p
YES
YES
NO
hsa-miR-218-5p
YES
YES
YES
hsa-miR-24-3p
YES
YES
NO
hsa-miR-27a-3p
YES
YES
YES
hsa-miR-27b-3p
YES
YES
YES
hsa-miR-28-5p
YES
YES
NO
hsa-miR-326
YES
YES
NO
hsa-miR-330-5p
YES
YES
NO
hsa-miR-488-3p
YES
YES
NO
hsa-miR-490-3p
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-708-5p
YES
YES
NO
hsa-miR-873-5p
YES
YES
NO
hsa-miR-96-5p
YES
YES
NO
Display: