ctcRbase

Entry Detail

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General Information

Database ID: SKCM09007 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SACM1L Full Name: SAC1 like phosphatidylinositide phosphatase Category: mRNA Synonyms: SAC1 Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 45689056 End Site(bp): 45745424 Gene Summary: This gene encodes an integral membrane protein, which is localized to the endoplasmic reticulum, and functions as a phosphoinositide phosphatase that hydrolyzes phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, and phosphatidylinositol 3,5-bisphosphate. Deletion of this gene in mouse results in preimplantation lethality. Other studies suggest that this gene is also involved in the organization of golgi membranes and mitotic spindles. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame, downstream translation termination codon via a stop codon readthrough mechanism.[provided by RefSeq, Dec 2017] External Links: Ensembl ID: ENSG00000211456 HGNC ID: HGNC:17059 Entrez Gene: 22908

Expression Profile of SACM1L Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-133a-3p YES YES NO hsa-miR-133b YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-145-5p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-708-5p YES YES NO hsa-miR-9-5p YES YES NO Display: