ctcRbase

Entry Detail

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General Information

Database ID: SKCM09055 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: AADAT Full Name: aminoadipate aminotransferase Category: mRNA Synonyms: KAT2|KATII|KYAT2 Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 170060222 End Site(bp): 170091699 Gene Summary: This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2013] External Links: Ensembl ID: ENSG00000109576 HGNC ID: HGNC:17929 Entrez Gene: 51166

Expression Profile of AADAT Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-497-5p YES YES NO Display: