ctcRbase

Entry Detail

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General Information

Database ID: SKCM09069 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ETV6 Full Name: ETS variant 6 Category: mRNA Synonyms: TEL|TEL/ABL|THC5 Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 11649854 End Site(bp): 11895402 Gene Summary: This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008] External Links: Ensembl ID: ENSG00000139083 HGNC ID: HGNC:3495 Entrez Gene: 2120

Expression Profile of ETV6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-129-5p YES NO YES hsa-miR-136-5p YES YES NO hsa-miR-137 YES YES NO hsa-miR-143-3p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-193a-3p YES YES YES hsa-miR-193b-3p YES YES YES hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-328-3p YES YES YES hsa-miR-340-5p YES NO YES hsa-miR-369-3p YES NO YES hsa-miR-374a-5p YES YES YES hsa-miR-374b-5p YES YES YES hsa-miR-410-3p YES NO YES hsa-miR-455-3p YES NO YES hsa-miR-653-5p YES YES NO hsa-miR-758-3p YES NO YES hsa-miR-873-5p YES YES NO Display: