ctcRbase

Entry Detail

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General Information

Database ID: SKCM09153 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: EFNA1 Full Name: ephrin A1 Category: mRNA Synonyms: B61|ECKLG|EFL1|EPLG1|LERK-1|LERK1|TNFAIP4 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 155127460 End Site(bp): 155134857 Gene Summary: This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000169242 HGNC ID: HGNC:3221 Entrez Gene: 1942

Expression Profile of EFNA1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES YES hsa-miR-145-5p YES YES YES hsa-miR-149-5p YES YES NO hsa-miR-183-5p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-21-5p YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-370-3p YES NO YES hsa-miR-429 YES YES YES hsa-miR-431-5p YES YES NO hsa-miR-485-5p YES YES YES hsa-miR-486-5p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-543 YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-9-5p YES NO YES hsa-miR-96-5p YES YES YES Display: