Entry Detail



General Information

Database ID:SKCM09198
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:FGF1
Full Name:fibroblast growth factor 1
Category:mRNA
Synonyms:AFGF|ECGF|ECGF-beta|ECGFA|ECGFB|FGF-1|FGF-alpha|FGFA|GLIO703|HBGF-1|HBGF1
Chromosome:chr5
Strand:-
Coordinate:
Start Site(bp):142592178End Site(bp):142698070
Gene Summary:The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]
External Links:
Ensembl ID:ENSG00000113578
HGNC ID:HGNC:3665
Entrez Gene:2246



Expression Profile of FGF1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-15a-5p
NO
YES
YES
hsa-miR-15b-5p
NO
YES
YES
hsa-miR-16-5p
NO
YES
YES
hsa-miR-195-5p
NO
YES
YES
hsa-miR-21-5p
YES
YES
NO
hsa-miR-365a-3p
NO
YES
YES
hsa-miR-424-5p
NO
YES
YES
hsa-miR-497-5p
NO
YES
YES
hsa-miR-590-5p
YES
YES
NO
hsa-miR-874-3p
NO
YES
YES
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