Entry Detail



General Information

Database ID:SKCM09225
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:NSMAF
Full Name:neutral sphingomyelinase activation associated factor
Category:mRNA
Synonyms:FAN|GRAMD5
Chromosome:chr8
Strand:-
Coordinate:
Start Site(bp):58583504End Site(bp):58659844
Gene Summary:This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]
External Links:
Ensembl ID:ENSG00000035681
HGNC ID:HGNC:8017
Entrez Gene:8439



Expression Profile of NSMAF Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-135a-5p
YES
YES
NO
hsa-miR-135b-5p
YES
YES
NO
hsa-miR-181a-5p
YES
YES
YES
hsa-miR-181b-5p
YES
YES
YES
hsa-miR-181c-5p
YES
YES
YES
hsa-miR-181d-5p
YES
YES
YES
hsa-miR-197-3p
YES
YES
NO
hsa-miR-224-5p
YES
YES
NO
hsa-miR-25-3p
YES
YES
YES
hsa-miR-299-3p
YES
YES
NO
hsa-miR-32-5p
YES
YES
YES
hsa-miR-329-3p
YES
YES
NO
hsa-miR-33a-5p
YES
YES
NO
hsa-miR-33b-5p
YES
YES
NO
hsa-miR-362-3p
YES
YES
NO
hsa-miR-363-3p
YES
YES
YES
hsa-miR-367-3p
YES
YES
YES
hsa-miR-451a
YES
YES
NO
hsa-miR-874-3p
YES
YES
NO
hsa-miR-92a-3p
YES
YES
YES
hsa-miR-92b-3p
YES
YES
YES
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