Entry Detail



General Information

Database ID:SKCM09246
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:KYAT1
Full Name:kynurenine aminotransferase 1
Category:mRNA
Synonyms:CCBL1|GTK|KAT1|KATI
Chromosome:chr9
Strand:-
Coordinate:
Start Site(bp):128832942End Site(bp):128882494
Gene Summary:This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000171097
HGNC ID:HGNC:1564
Entrez Gene:883



Expression Profile of KYAT1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-154-5p
YES
YES
NO
hsa-miR-185-5p
YES
YES
NO
hsa-miR-543
YES
YES
NO
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