ctcRbase

Entry Detail

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General Information

Database ID: SKCM09276 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TULP3 Full Name: tubby like protein 3 Category: mRNA Synonyms: TUBL3 Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 2877223 End Site(bp): 2941140 Gene Summary: This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2009] External Links: Ensembl ID: ENSG00000078246 HGNC ID: HGNC:12425 Entrez Gene: 7289

Expression Profile of TULP3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-132-3p YES YES NO hsa-miR-137 YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-143-3p YES YES NO hsa-miR-147a YES NO NO hsa-miR-194-5p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-22-3p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-429 YES YES NO hsa-miR-491-5p YES YES NO Display: