ctcRbase

Entry Detail

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General Information

Database ID: SKCM09277 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ARHGDIB Full Name: Rho GDP dissociation inhibitor beta Category: mRNA Synonyms: D4|GDIA2|GDID4|LYGDI|Ly-GDI|RAP1GN1|RhoGDI2 Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 14942017 End Site(bp): 14961728 Gene Summary: Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM, Dec 2010]398 External Links: Ensembl ID: ENSG00000111348 HGNC ID: HGNC:679 Entrez Gene: 397

Expression Profile of ARHGDIB Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-186-5p YES YES NO hsa-miR-219a-5p YES YES NO hsa-miR-328-3p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-375 YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-599 YES YES NO Display: