ctcRbase

Entry Detail

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General Information

Database ID: SKCM09279 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ITGA5 Full Name: integrin subunit alpha 5 Category: mRNA Synonyms: CD49e|FNRA|VLA-5|VLA5A Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 54395261 End Site(bp): 54419460 Gene Summary: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015] External Links: Ensembl ID: ENSG00000161638 HGNC ID: HGNC:6141 Entrez Gene: 3678

Expression Profile of ITGA5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-128-3p YES YES YES hsa-miR-1297 YES YES YES hsa-miR-137 YES NO YES hsa-miR-143-3p YES YES NO hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-149-5p YES YES NO hsa-miR-152-3p YES YES YES hsa-miR-153-3p YES YES NO hsa-miR-205-5p YES NO YES hsa-miR-22-3p YES YES NO hsa-miR-25-3p YES YES YES hsa-miR-26a-5p YES YES YES hsa-miR-26b-5p YES YES YES hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-28-5p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-32-5p YES YES YES hsa-miR-326 YES YES YES hsa-miR-328-3p YES YES YES hsa-miR-330-5p YES YES YES hsa-miR-338-3p YES YES NO hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-382-5p YES YES NO hsa-miR-384 YES YES NO hsa-miR-708-5p YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES Display: