ncRNA Symbol: | SART3 |
Full Name: | spliceosome associated factor 3, U4/U6 recycling protein |
Category: | mRNA |
Synonyms: | DSAP1|P100|RP11-13G14|TIP110|p110|p110(nrb) |
Chromosome: | chr12 |
Strand: | - |
Coordinate: | Start Site(bp): | 108522580 | End Site(bp): | 108561400 | |
Gene Summary: | The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. [provided by RefSeq, Jul 2008] |
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