Entry Detail



General Information

Database ID:SKCM09283
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:FBXO21
Full Name:F-box protein 21
Category:mRNA
Synonyms:FBX21
Chromosome:chr12
Strand:-
Coordinate:
Start Site(bp):117141988End Site(bp):117190531
Gene Summary:This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000135108
HGNC ID:HGNC:13592
Entrez Gene:23014



Expression Profile of FBXO21 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-103a-3p
YES
NO
NO
hsa-miR-106a-5p
YES
YES
YES
hsa-miR-106b-5p
YES
YES
YES
hsa-miR-107
YES
NO
NO
hsa-miR-1271-5p
YES
YES
NO
hsa-miR-128-3p
YES
YES
YES
hsa-miR-132-3p
YES
YES
YES
hsa-miR-140-3p
YES
NO
YES
hsa-miR-142-3p
YES
YES
YES
hsa-miR-142-5p
YES
NO
YES
hsa-miR-150-5p
YES
YES
NO
hsa-miR-15a-5p
YES
YES
YES
hsa-miR-15b-5p
YES
YES
YES
hsa-miR-16-5p
YES
NO
YES
hsa-miR-17-5p
YES
YES
YES
hsa-miR-182-5p
YES
YES
NO
hsa-miR-186-5p
YES
YES
NO
hsa-miR-195-5p
YES
YES
YES
hsa-miR-197-3p
YES
YES
NO
hsa-miR-200b-3p
YES
YES
NO
hsa-miR-200c-3p
YES
YES
NO
hsa-miR-20a-5p
YES
YES
YES
hsa-miR-20b-5p
YES
YES
YES
hsa-miR-212-3p
YES
YES
YES
hsa-miR-214-3p
YES
NO
NO
hsa-miR-217
YES
YES
NO
hsa-miR-24-3p
YES
YES
NO
hsa-miR-300
YES
YES
NO
hsa-miR-30a-5p
YES
YES
NO
hsa-miR-30b-5p
YES
YES
NO
hsa-miR-30c-5p
YES
YES
NO
hsa-miR-30d-5p
YES
YES
NO
hsa-miR-30e-5p
YES
YES
NO
hsa-miR-340-5p
YES
YES
YES
hsa-miR-367-3p
YES
YES
NO
hsa-miR-377-3p
YES
YES
NO
hsa-miR-381-3p
YES
YES
NO
hsa-miR-382-5p
YES
YES
NO
hsa-miR-424-5p
YES
NO
YES
hsa-miR-429
YES
YES
NO
hsa-miR-433-3p
YES
YES
NO
hsa-miR-497-5p
YES
NO
YES
hsa-miR-503-5p
YES
NO
YES
hsa-miR-519d-3p
YES
YES
YES
hsa-miR-543
YES
YES
YES
hsa-miR-93-5p
YES
YES
YES
hsa-miR-96-5p
YES
YES
NO
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