Entry Detail



General Information

Database ID:SKCM09321
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:FECH
Full Name:ferrochelatase
Category:mRNA
Synonyms:EPP|EPP1|FCE
Chromosome:chr18
Strand:-
Coordinate:
Start Site(bp):57548283End Site(bp):57586772
Gene Summary:The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.[provided by RefSeq, May 2010]
External Links:
Ensembl ID:ENSG00000066926
HGNC ID:HGNC:3647
Entrez Gene:2235



Expression Profile of FECH Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-130a-3p
YES
YES
NO
hsa-miR-130b-3p
YES
YES
NO
hsa-miR-140-5p
YES
YES
YES
hsa-miR-186-5p
YES
YES
YES
hsa-miR-19a-3p
YES
YES
NO
hsa-miR-19b-3p
YES
YES
NO
hsa-miR-23b-3p
YES
YES
NO
hsa-miR-301a-3p
YES
YES
NO
hsa-miR-301b-3p
YES
YES
NO
hsa-miR-374a-5p
YES
YES
YES
hsa-miR-374b-5p
YES
YES
YES
hsa-miR-376c-3p
YES
YES
NO
hsa-miR-383-5p
YES
NO
YES
hsa-miR-454-3p
YES
YES
NO
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