ctcRbase

Entry Detail

---



General Information

Database ID: SKCM09331 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: BCL2L12 Full Name: BCL2 like 12 Category: mRNA Synonyms: - Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 49665142 End Site(bp): 49673916 Gene Summary: This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] External Links: Ensembl ID: ENSG00000126453 HGNC ID: HGNC:13787 Entrez Gene: 83596

Expression Profile of BCL2L12 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-1271-5p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-7-5p YES YES NO hsa-miR-96-5p YES YES NO Display: