Entry Detail



General Information

Database ID:SKCM09337
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:TASP1
Full Name:taspase 1
Category:mRNA
Synonyms:C20orf13|dJ585I14.2
Chromosome:chr20
Strand:-
Coordinate:
Start Site(bp):13389392End Site(bp):13638940
Gene Summary:This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000089123
HGNC ID:HGNC:15859
Entrez Gene:55617



Expression Profile of TASP1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-148a-3p
YES
YES
NO
hsa-miR-148b-3p
YES
YES
NO
hsa-miR-152-3p
YES
YES
NO
hsa-miR-15a-5p
YES
YES
YES
hsa-miR-15b-5p
YES
YES
YES
hsa-miR-16-5p
YES
YES
YES
hsa-miR-195-5p
YES
YES
YES
hsa-miR-30a-5p
YES
YES
YES
hsa-miR-30b-5p
YES
YES
YES
hsa-miR-30c-5p
YES
YES
YES
hsa-miR-30d-5p
YES
YES
YES
hsa-miR-30e-5p
YES
YES
YES
hsa-miR-340-5p
YES
YES
NO
hsa-miR-342-3p
YES
YES
NO
hsa-miR-377-3p
YES
YES
NO
hsa-miR-424-5p
YES
YES
YES
hsa-miR-497-5p
YES
YES
YES
hsa-miR-599
YES
YES
NO
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