ctcRbase

Entry Detail

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General Information

Database ID: SKCM09349 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: BEX2 Full Name: brain expressed X-linked 2 Category: mRNA Synonyms: BEX1|DJ79P11.1 Chromosome: chrX Strand: - Coordinate: Start Site(bp): 103309346 End Site(bp): 103311046 Gene Summary: This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009] External Links: Ensembl ID: ENSG00000133134 HGNC ID: HGNC:30933 Entrez Gene: 84707

Expression Profile of BEX2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-138-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-543 YES YES NO Display: