exRNAdisease

Entry Detail

---



General Information

Database ID: exR0017412 RNA Name: AFF3 RNA Type: mRNA Chromosome: chr2 Starnd: - Coordinate: Start Site(bp): 99545419 End Site(bp): 100192428 External Links: ENSG00000144218

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC135050.2 chr16 31083439 31094956 - ALG8 chr11 78100936 78139653 - CCNF chr16 2429394 2458854 + CEP170 chr1 243124428 243255348 - CERS5 chr12 50129289 50167533 - FBXL19 chr16 30923055 30948783 + FOXP2 chr7 114086327 114693772 + GNB2 chr7 100673567 100679174 + HDDC3 chr15 90929964 90935196 - HMGA2 chr12 65824131 65966295 + HS6ST1 chr2 128236716 128318868 - INTS7 chr1 211940399 212035557 - JRK chr8 142657460 142681968 - MECOM chr3 169083499 169663775 - NISCH chr3 52455118 52493068 + SIPA1L3 chr19 37907208 38208369 + TMEM250 chr9 136114581 136118875 - VKORC1 chr16 31090842 31095980 - ZBED4 chr22 49853844 49890080 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-33a-5p chr22 41900949 41900969 + hsa-miR-520d-5p chr19 53720111 53720130 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC026471.1 chr16 31456711 31459736 - Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA