exRNAdisease

Entry Detail

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General Information

Database ID: exR0017793 RNA Name: AP3D1 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 2100988 End Site(bp): 2164468 External Links: ENSG00000065000

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCA3 chr16 2275881 2340746 - ABL1 chr9 130713016 130887675 + AC008397.2 chr19 18207961 18255419 - AC010422.5 chr19 12664828 12669397 - AC138894.1 chr16 28456371 28492098 - ACACA chr17 37084992 37406836 - ACOT7 chr1 6264269 6394391 - ACSS1 chr20 25006230 25058980 - ACTB chr7 5527148 5563784 - ACTN4 chr19 38647649 38731589 + ADAM10 chr15 58588809 58749791 - ADGRL1 chr19 14147743 14206187 - AGAP3 chr7 151085831 151144436 + AGPAT3 chr21 43865223 43987592 + AL121845.3 chr20 63708864 63739103 + AL713999.1 chr1 155169409 155187272 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-21-5p chr17 59841273 59841294 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC019205.1 chr6 73263212 73301789 + AC026362.1 chr12 122975320 122982907 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA