exRNAdisease

Entry Detail

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General Information

Database ID: exR0017831 RNA Name: APLP2 RNA Type: mRNA Chromosome: chr11 Starnd: + Coordinate: Start Site(bp): 130068147 End Site(bp): 130144811 External Links: ENSG00000084234

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCA2 chr9 137007234 137028922 - ABCB8 chr7 151028422 151047782 + ABR chr17 1003518 1229738 - ABRACL chr6 139028745 139043302 + AC010422.3 chr19 12643831 12648397 - AC015813.2 chr17 57989038 58007246 - AC138811.2 chr16 18788063 18801519 - AC245033.1 chr15 82536788 82573194 - ADAR chr1 154582057 154628013 - AGK chr7 141551278 141655244 + AL021546.1 chr12 120438198 120460006 + AL136454.1 chr1 192716132 192716653 + AL160269.1 chr9 96235331 96352058 - ALDH9A1 chr1 165662216 165698863 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-671-5p chr7 151238449 151238471 + hsa-miR-423-5p chr17 30117095 30117117 + hsa-miR-1294 chr5 154347153 154347174 + hsa-miR-3654 chr7 133034860 133034878 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC026362.1 chr12 122975320 122982907 + AC067852.1 chr17 42536510 42562062 + AC245033.4 chr15 82533175 82540008 - Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA