exRNAdisease

Entry Detail

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General Information

Database ID: exR0018042 RNA Name: ARPP19 RNA Type: mRNA Chromosome: chr15 Starnd: - Coordinate: Start Site(bp): 52547045 End Site(bp): 52569883 External Links: ENSG00000128989

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCD1 chrX 153724856 153744755 + ABL2 chr1 179099330 179229684 - AC010422.3 chr19 12643831 12648397 - ACAT2 chr6 159762045 159779112 + ACTG1 chr17 81509971 81523847 - AHCYL2 chr7 129225023 129430211 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-24-3p chr9 95086064 95086085 + hsa-miR-105-5p chrX 152394458 152394480 - hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-135a-5p chr12 97563834 97563856 + hsa-miR-34c-5p chr11 111513451 111513473 + hsa-miR-323a-3p chr14 101025782 101025802 + hsa-miR-135b-5p chr1 205448361 205448383 - hsa-miR-3654 chr7 133034860 133034878 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC078881.1 chr4 177442519 177681381 + AC132217.1 chr11 2129121 2129964 - AL137230.2 chr14 89628921 89642671 - Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA