exRNAdisease

Entry Detail

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General Information

Database ID: exR0018261 RNA Name: ATXN2L RNA Type: mRNA Chromosome: chr16 Starnd: + Coordinate: Start Site(bp): 28823035 End Site(bp): 28837237 External Links: ENSG00000168488

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005726.1 chr17 28455752 28614185 - AC011511.4 chr19 10315471 10320678 - ADA chr20 44619522 44652233 - ADAMTS10 chr19 8580240 8610735 - AKTIP chr16 53491040 53504411 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-184 chr15 79209840 79209861 + hsa-miR-424-5p chrX 134546680 134546701 - hsa-miR-449a chr5 55170586 55170607 - hsa-miR-650 chr22 22822791 22822811 + hsa-miR-449b-5p chr5 55170706 55170727 - hsa-miR-423-5p chr17 30117095 30117117 + hsa-miR-708-5p chr11 79402077 79402099 - hsa-miR-1286 chr22 20249145 20249165 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC027307.3 chr19 1440839 1441938 + Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA