exRNAdisease

Entry Detail

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General Information

Database ID: exR0018932 RNA Name: CA12 RNA Type: mRNA Chromosome: chr15 Starnd: - Coordinate: Start Site(bp): 63321378 End Site(bp): 63381846 External Links: ENSG00000074410

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ADPRHL2 chr1 36088892 36093932 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-101-3p chr1 65058442 65058462 - hsa-miR-103a-3p chr5 168560904 168560926 - hsa-miR-204-5p chr9 70810031 70810052 - hsa-miR-211-5p chr15 31065095 31065116 - hsa-miR-195-5p chr17 7017667 7017687 - hsa-miR-324-5p chr17 7223343 7223364 - hsa-miR-431-5p chr14 100881026 100881046 + hsa-miR-432-5p chr14 100884496 100884518 + hsa-miR-520a-5p chr19 53690895 53690915 + hsa-miR-525-5p chr19 53697547 53697567 + hsa-miR-362-3p chrX 50009005 50009026 + hsa-miR-628-5p chr15 55372991 55373012 - hsa-miR-1278 chr1 193136552 193136573 + circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA