exRNAdisease

Entry Detail

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General Information

Database ID: exR0019379 RNA Name: CD151 RNA Type: mRNA Chromosome: chr11 Starnd: + Coordinate: Start Site(bp): 832887 End Site(bp): 839831 External Links: ENSG00000177697

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC120057.2 chr17 7240427 7244635 - AGBL5 chr2 27042364 27070622 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-148a-3p chr7 25949922 25949943 - hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-130a-3p chr11 57641252 57641273 + hsa-miR-34c-5p chr11 111513451 111513473 + hsa-miR-301a-3p chr17 59151149 59151171 - hsa-miR-130b-3p chr22 21653354 21653375 + hsa-miR-449a chr5 55170586 55170607 - hsa-miR-491-5p chr9 20716120 20716141 + hsa-miR-449b-5p chr5 55170706 55170727 - hsa-miR-454-3p chr17 59137787 59137809 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA