exRNAdisease

Entry Detail

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General Information

Database ID: exR0019405 RNA Name: CD276 RNA Type: mRNA Chromosome: chr15 Starnd: + Coordinate: Start Site(bp): 73683966 End Site(bp): 73714514 External Links: ENSG00000103855

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008878.3 chr19 7382834 7470241 + AC245033.1 chr15 82536788 82573194 - ACACA chr17 37084992 37406836 - ACLY chr17 41866917 41930542 - ACTR10 chr14 58200080 58235636 + ADNP chr20 50888916 50931437 - AGRN chr1 1020120 1056118 + ALDH1B1 chr9 38392702 38398661 + ALDH7A1 chr5 126531200 126595362 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-185-5p chr22 20033153 20033174 + hsa-miR-513a-5p chrX 147213538 147213555 - hsa-miR-665 chr14 100875075 100875094 + hsa-miR-873-5p chr9 28888925 28888945 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC048341.2 chr12 62603909 62604399 + AC132217.1 chr11 2129121 2129964 - AC245033.4 chr15 82533175 82540008 - Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA