exRNAdisease

Entry Detail

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General Information

Database ID: exR0019733 RNA Name: CGN RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 151510510 End Site(bp): 151538692 External Links: ENSG00000143375

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007040.2 chr2 70939318 70995336 - AC067968.1 chr19 44025354 44087318 + ACIN1 chr14 23058564 23095614 - ACTA1 chr1 229431245 229434098 - ADNP2 chr18 80109262 80147523 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-24-3p chr9 95086064 95086085 + hsa-miR-138-5p chr16 56858527 56858549 + hsa-miR-320a-3p chr8 22244975 22244996 - hsa-miR-302d-3p chr4 112648006 112648028 - hsa-miR-367-3p chr4 112647877 112647898 - hsa-miR-320b chr1 224257049 224257070 - hsa-miR-320c chr18 24321716 24321735 + hsa-miR-320d chr13 40727828 40727846 - hsa-miR-198 chr3 120395703 120395724 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA