exRNAdisease

Entry Detail

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General Information

Database ID: exR0019875 RNA Name: CIT RNA Type: mRNA Chromosome: chr12 Starnd: - Coordinate: Start Site(bp): 119685791 End Site(bp): 119877320 External Links: ENSG00000122966

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAMP chr2 218264123 218270257 - AATF chr17 36948954 37056871 + AC004922.1 chr7 99325879 99394653 + AC010547.4 chr16 71447600 71489311 - ACVR1 chr2 157736444 157876330 - AKT2 chr19 40230317 40285536 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-143-3p chr5 149428978 149428998 + hsa-miR-520a-3p chr19 53690933 53690954 + hsa-miR-519a-3p chr19 53762397 53762418 + hsa-miR-454-3p chr17 59137787 59137809 - hsa-miR-1276 chr15 85770548 85770567 - hsa-miR-4750-5p chr19 49888177 49888198 + hsa-miR-4750-3p chr19 49888209 49888230 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC079414.3 chr16 78123243 78124332 + Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA