exRNAdisease

Entry Detail

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General Information

Database ID: exR0020209 RNA Name: CORO1C RNA Type: mRNA Chromosome: chr12 Starnd: - Coordinate: Start Site(bp): 108645109 End Site(bp): 108731596 External Links: ENSG00000110880

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC245033.1 chr15 82536788 82573194 - ACTB chr7 5527148 5563784 - ADK chr10 74151202 74709963 + AKAP1 chr17 57085092 57121346 + AL022238.4 chr22 40346529 40410054 + AL928654.3 chr14 105487199 105492267 + ALDH9A1 chr1 165662216 165698863 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-211-5p chr15 31065095 31065116 - hsa-miR-449a chr5 55170586 55170607 - hsa-miR-449b-5p chr5 55170706 55170727 - hsa-miR-140-3p chr16 69933142 69933162 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC017116.1 chr7 44064908 44066079 + AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA