exRNAdisease

Entry Detail

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General Information

Database ID: exR0020378 RNA Name: CS RNA Type: mRNA Chromosome: chr12 Starnd: - Coordinate: Start Site(bp): 56271699 End Site(bp): 56300391 External Links: ENSG00000062485

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAMP chr2 218264123 218270257 - ABCB9 chr12 122920951 122981649 - ABHD10 chr3 111979010 111993368 + AC004922.1 chr7 99325879 99394653 + AC073896.1 chr12 56285916 56316059 - AC138811.2 chr16 18788063 18801519 - ACTR2 chr2 65227753 65271253 + AHCYL1 chr1 109984765 110023742 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-196a-5p chr17 48632532 48632553 - hsa-miR-196b-5p chr7 27169528 27169549 - hsa-miR-431-5p chr14 100881026 100881046 + hsa-miR-654-5p chr14 101040234 101040255 + hsa-miR-198 chr3 120395703 120395724 - hsa-miR-5001-5p chr2 232550530 232550553 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007218.1 chr16 9666885 9676843 - AC008267.5 chr7 66493607 66495758 + AC040977.2 chr17 6985494 7019414 - AC115284.1 chr3 51961212 51974031 - AL031595.3 chr22 44139365 44153626 + Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA