exRNAdisease

Entry Detail

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General Information

Database ID: exR0020406 RNA Name: CSNK1E RNA Type: mRNA Chromosome: chr22 Starnd: - Coordinate: Start Site(bp): 38290691 End Site(bp): 38318084 External Links: ENSG00000213923

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010422.3 chr19 12643831 12648397 - AC091167.2 chr15 90249556 90272208 + AC138969.1 chr16 16317444 16350590 + ACAP3 chr1 1292390 1309609 - ACBD3 chr1 226144679 226186741 - ACTG1 chr17 81509971 81523847 - ADCY1 chr7 45574140 45723116 + ADGRB2 chr1 31727117 31764893 - AFF1 chr4 86935002 87141054 + AGPAT2 chr9 136673143 136687457 - AKAP10 chr17 19904302 19978343 - AKR1B1 chr7 134442356 134459284 - AL157392.5 chr10 13610047 13655929 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-let-7d-5p chr9 94178841 94178862 + hsa-miR-491-5p chr9 20716120 20716141 + hsa-miR-541-3p chr14 101064548 101064569 + hsa-miR-873-5p chr9 28888925 28888945 - hsa-miR-1286 chr22 20249145 20249165 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AC132872.1 chr17 82293716 82294910 + AL049543.1 chr6 28587378 28591747 + Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA