Entry Detail



General Information

Database ID:exR0020767
RNA Name:DCTN4
RNA Type:mRNA
Chromosome:chr5
Starnd:-
Coordinate:
Start Site(bp):150708440End Site(bp):150759109
External Links:ENSG00000132912



Disease Information

Disease Name:Trisomy 18 Syndrome
Disease Category:Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH ID:D000073842
Type:Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Alias:Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome



Expression Detail

GEO ID:GSE25634
Description:Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls
Experimental Design:Disease vs Control
Case Disease Type:Trisomy 18 Syndrome
Case Disease SubType:NA
Case Sample:Trisomy 18 Syndrome
Control Sample:Normal
Number of Case:5
Number of Control:6
Number of Samples:11





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004223.3
chr17
35011349
35121493
-
AC010422.3
chr19
12643831
12648397
-
ACAT2
chr6
159762045
159779112
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
AK4
chr1
65147549
65232145
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-27a-3p
chr19
13836447
13836467
-
hsa-miR-27b-3p
chr9
95085505
95085525
+
hsa-miR-532-5p
chrX
50003167
50003188
+
hsa-miR-421
chrX
74218392
74218414
-
hsa-miR-769-5p
chr19
46018961
46018982
+
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:GSE25634
Sample Source:Amniotic Fluid
Source Fraction:Supernatant
Platform:GPL570
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:17063
Sample treatment protocol:NA
RNA Extract protocol:RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform.
RNA library preparation protocol:biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).



Reference

PMID:NA
Title:NA
Author:NA
Journal:NA
Description:NA