exRNAdisease

Entry Detail

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General Information

Database ID: exR0020817 RNA Name: DDX3X RNA Type: mRNA Chromosome: chrX Starnd: + Coordinate: Start Site(bp): 41333284 End Site(bp): 41364472 External Links: ENSG00000215301

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AATF chr17 36948954 37056871 + AC011455.2 chr19 38915404 38949855 - AC018523.2 chr11 14493783 14520344 - AC023055.1 chr12 55757275 55827546 - AC245033.1 chr15 82536788 82573194 - ACAP3 chr1 1292390 1309609 - ADGRG6 chr6 142301854 142446266 + AIF1L chr9 131096476 131123152 + AK2 chr1 33007940 33080996 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-217-5p chr2 55983020 55983042 - hsa-miR-186-5p chr1 71067681 71067702 - hsa-miR-490-3p chr7 136903242 136903263 + hsa-miR-514a-3p chrX 147281957 147281977 - hsa-miR-513c-5p chrX 147189753 147189774 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012236.1 chr15 31221999 31230838 - AC020663.1 chr16 4730115 4752565 - AC021078.1 chr5 149494314 149504670 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA