exRNAdisease

Entry Detail

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General Information

Database ID: exR0021490 RNA Name: EIF4G1 RNA Type: mRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 184314495 End Site(bp): 184335358 External Links: ENSG00000114867

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCB8 chr7 151028422 151047782 + ABL1 chr9 130713016 130887675 + ABL2 chr1 179099330 179229684 - AC010422.3 chr19 12643831 12648397 - AC011455.2 chr19 38915404 38949855 - AC025165.3 chr12 57772660 57797554 + AC137834.1 chr12 57249609 57296484 - ACTB chr7 5527148 5563784 - ACTR2 chr2 65227753 65271253 + ADAMTS1 chr21 26835755 26845409 - ADGRV1 chr5 90529344 91164437 + AIDA chr1 222668013 222713210 - AK2 chr1 33007940 33080996 - AKAP12 chr6 151239967 151358559 + AKAP8L chr19 15380050 15419141 - AKIRIN2 chr6 87674860 87702233 - AKT2 chr19 40230317 40285536 - ALCAM chr3 105366909 105576900 + ALDH3A2 chr17 19648136 19685760 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-6797-3p chr19 41869675 41869696 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008124.1 chr12 45718046 45727775 - AC124068.2 chr15 89335053 89336161 + AC245014.3 chr1 145281116 145281462 + AL096870.2 chr14 24209646 24215987 - Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA