exRNAdisease

Entry Detail

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General Information

Database ID: exR0022276 RNA Name: FKBP1A RNA Type: mRNA Chromosome: chr20 Starnd: - Coordinate: Start Site(bp): 1368978 End Site(bp): 1393172 External Links: ENSG00000088832

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AASS chr7 122073549 122144255 - ABL1 chr9 130713016 130887675 + AC004922.1 chr7 99325879 99394653 + AC068580.4 chr11 1734821 1763954 - AC073508.2 chr17 40627356 40665141 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADAM19 chr5 157395534 157575775 - AFAP1 chr4 7758714 7939926 - AIG1 chr6 143060496 143341058 + AKT1 chr14 104769349 104795751 - AL136531.2 chr20 1317571 1393096 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-18a-5p chr13 91350756 91350778 + hsa-miR-650 chr22 22822791 22822811 + hsa-miR-541-3p chr14 101064548 101064569 + hsa-miR-665 chr14 100875075 100875094 + hsa-miR-1321 chrX 85835832 85835849 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC025181.2 chr5 32174471 32175272 + Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA