exRNAdisease

Entry Detail

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General Information

Database ID: exR0022299 RNA Name: FLOT2 RNA Type: mRNA Chromosome: chr17 Starnd: - Coordinate: Start Site(bp): 28879335 End Site(bp): 28897733 External Links: ENSG00000132589

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008695.1 chr5 131425891 131796983 - AC048338.1 chr12 122207779 122266423 - AC245033.1 chr15 82536788 82573194 - ACTG1 chr17 81509971 81523847 - AGFG1 chr2 227472152 227561214 + AHCY chr20 34280268 34311802 - AIP chr11 67483026 67491103 + AK4 chr1 65147549 65232145 + AKAP12 chr6 151239967 151358559 + AL136454.1 chr1 192716132 192716653 + AL138752.2 chr9 37588413 38068687 - AL355987.3 chr9 136791379 136800595 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-15a-5p chr13 50049167 50049188 - hsa-miR-16-5p chr3 160404754 160404775 + hsa-miR-15b-5p chr3 160404607 160404628 + hsa-miR-185-5p chr22 20033153 20033174 + hsa-miR-195-5p chr17 7017667 7017687 - hsa-miR-424-5p chrX 134546680 134546701 - hsa-miR-5100 chr10 42997630 42997651 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC245033.4 chr15 82533175 82540008 - Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA