exRNAdisease

Entry Detail

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General Information

Database ID: exR0022386 RNA Name: FOXP1 RNA Type: mRNA Chromosome: chr3 Starnd: - Coordinate: Start Site(bp): 70952817 End Site(bp): 71583993 External Links: ENSG00000114861

Disease Information

Disease Name: Trisomy 18 Syndrome Disease Category: Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH ID: D000073842 Type: Diseases Category/Congenital, Hereditary, and Neonatal Diseases and Abnormalities Alias: Trisomy 18 Syndromes//Trisomy E Syndrome//Complete Trisomy 18 Syndrome//Edwards Syndrome//Trisomy 18//Mosaic Trisomy 18 Syndrome

Expression Detail

GEO ID: GSE25634 Description: Expression profiles of amniotic fluid from human fetuses with Trisomy 18 and euploid controls Experimental Design: Disease vs Control Case Disease Type: Trisomy 18 Syndrome Case Disease SubType: NA Case Sample: Trisomy 18 Syndrome Control Sample: Normal Number of Case: 5 Number of Control: 6 Number of Samples: 11

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010422.3 chr19 12643831 12648397 - AC093525.2 chr16 2496032 2520218 + ADCY9 chr16 3953387 4116442 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-22-3p chr17 1713914 1713935 - hsa-miR-222-3p chrX 45747036 45747056 - hsa-miR-130a-3p chr11 57641252 57641273 + hsa-miR-149-5p chr2 240456015 240456037 + hsa-miR-206 chr6 52144401 52144422 + hsa-miR-200c-3p chr12 6963742 6963764 + hsa-miR-367-3p chr4 112647877 112647898 - hsa-miR-339-5p chr7 1022990 1023012 - hsa-miR-384 chrX 76919285 76919304 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: GSE25634 Sample Source: Amniotic Fluid Source Fraction: Supernatant Platform: GPL570 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 17063 Sample treatment protocol: NA RNA Extract protocol: RNA was extracted from 10 mL amniotic fluid supernatant with 30 mL TRIzol LS Reagent (Invitrogen, Carlsbad, CA) and 8 mL chloroform. RNA library preparation protocol: biotin Samples were labeled using the FL-Ovation™ cDNA Biotin Module V2 (NuGEN, San Carlos, CA).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA